Mon. 11
Tue. 12
Wed. 13
Thu. 14
Fri. 15
09:00
10:00
11:00
12:00
13:00
14:00
15:00
16:00
17:00
18:00
19:00
20:00
21:00
22:00
Arrival and Registration
15:00 - 17:00 (2h)
Arrival and Registration
Welcome and introduction
17:00 - 17:30 (30min)
Welcome and introduction
Engineering organoids-on-a-chip
17:30 - 18:30 (1h)
Engineering organoids-on-a-chip
Matthias Lutolf (EMBO keynote speaker)
Session I : Organoids
Self-organization in pancreas organoids: from complex ductal networks to differentiation
Multiscale Immuno-Oncology on-Chip shows collective T cell behavior drives tumor regression
Engineering solutions for kidney organoids derived from human pluripotent stem cells
Coffee break
Organoid zoo reveals mechanisms for species-specific time
Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
Structuration and culture of brain derived spheroids in acoustic levitation
9:00 - 12:10 (3h10)
Session I : Organoids
Session I : Organoids
9:00 - 9:40 (40min)
Self-organization in pancreas organoids: from complex ductal networks to differentiation
Anne Grapin-Botton
9:40 - 9:55 (15min)
Multiscale Immuno-Oncology on-Chip shows collective T cell behavior drives tumor regression
Shreyansh Jain
9:55 - 10:35 (40min)
Engineering solutions for kidney organoids derived from human pluripotent stem cells
Nuria Montserrat (EMBO Young Investigator Lecture)
10:35 - 11:00 (25min)
Coffee break
11:00 - 11:40 (40min)
Organoid zoo reveals mechanisms for species-specific time
Miki Ebisuya
11:40 - 11:55 (15min)
Spatiotemporal dynamics of self-organized branching in pancreas-derived organoids
Samuel Randriamanantsoa
11:55 - 12:10 (15min)
Structuration and culture of brain derived spheroids in acoustic levitation
Chloé Dupuis
Cell-state transitions and collective cell movement in embryonic organoids
12:10 - 12:50 (40min)
Cell-state transitions and collective cell movement in embryonic organoids
Pierre-François Lenne
Lunch
12:50 - 13:40 (50min)
Lunch
Poster Session I
13:40 - 15:40 (2h)
Poster Session I
Session II : Sensing & Probing
Chemically-selective and non-invasive analysis of organoid cultures - A new approach
Long-term live imaging and multiscale analysis of human organoids
Coffee break
Advanced integrated optical oxygen, pH and glucose sensors for microfluidic and organ on chip application
Cell induced collagen matrix remodeling monitored by interstitial flow metrology
JeWells Platform: Quantitative 3D imaging of organoids and microphysiological elements.
15:40 - 18:10 (2h30)
Session II : Sensing & Probing
15:40 - 15:55 (15min)
Chemically-selective and non-invasive analysis of organoid cultures - A new approach
Nathalie Jung
15:55 - 16:35 (40min)
Long-term live imaging and multiscale analysis of human organoids
Francesco Pampaloni
16:35 - 17:00 (25min)
Coffee break
17:00 - 17:40 (40min)
Advanced integrated optical oxygen, pH and glucose sensors for microfluidic and organ on chip application
Torsten Mayr
17:40 - 17:55 (15min)
Cell induced collagen matrix remodeling monitored by interstitial flow metrology
Jean Cacheux
17:55 - 18:10 (15min)
JeWells Platform: Quantitative 3D imaging of organoids and microphysiological elements.
Anne Beghin
Session III - Organ-on-Chips
Engineering 3D models of physiology and disease: Lessons from Chapter One
A 3D colon on chip to study the peristalsis influence on the physiopathological cellular ecosystem
Epithelial mechanobiology from the bottom up
Coffee break
3D to 2D: Evolution of organoid culture systems to study intestinal physiology and disease
High-throughput tumor-on-chip to study micro-pancreatic tumors under mechanical compression
MyoChip: building an innervated and irrigated muscle-on-chip
9:00 - 12:10 (3h10)
Session III - Organ-on-Chips
Stéphanie Descroix
9:00 - 9:40 (40min)
Engineering 3D models of physiology and disease: Lessons from Chapter One
Christopher Chen
9:40 - 9:55 (15min)
A 3D colon on chip to study the peristalsis influence on the physiopathological cellular ecosystem
Moencopi Bernheim-Dennery
9:55 - 10:35 (40min)
Epithelial mechanobiology from the bottom up
Xavier Trepat
10:35 - 11:00 (25min)
Coffee break
11:00 - 11:40 (40min)
3D to 2D: Evolution of organoid culture systems to study intestinal physiology and disease
Scott Magness
11:40 - 11:55 (15min)
High-throughput tumor-on-chip to study micro-pancreatic tumors under mechanical compression
Tiphaine Matéo
11:55 - 12:10 (15min)
MyoChip: building an innervated and irrigated muscle-on-chip
Katharina Hennig
Lunch
12:10 - 13:30 (1h20)
Lunch
Excursion
13:30 - 18:00 (4h30)
Excursion
Session IV : Theory / modeling
Physics of 3D cell aggregates
Self-organized tissue mechanics underlie embryonic regulation
Topological control of tissue morphogenesis
Coffee break
Mechanochemical bistability in intestinal organoids
Tissue fluidization by cell-shape-controlled active stresses
Curvature induces active velocity waves in rotating cancer organoids
9:00 - 12:10 (3h10)
Session IV : Theory / modeling
Edouard Hannezo
9:00 - 9:40 (40min)
Physics of 3D cell aggregates
Guillaume Salbreux
9:40 - 9:55 (15min)
Self-organized tissue mechanics underlie embryonic regulation
Alexander Chamolly
9:55 - 10:35 (40min)
Topological control of tissue morphogenesis
Keisuke Ishihara
10:35 - 11:00 (25min)
Coffee break
11:00 - 11:40 (40min)
Mechanochemical bistability in intestinal organoids
Edouard Hannezo
11:40 - 11:55 (15min)
Tissue fluidization by cell-shape-controlled active stresses
Lin Shaozhen
11:55 - 12:10 (15min)
Curvature induces active velocity waves in rotating cancer organoids
David Brueckner
Lunch
12:10 - 13:00 (50min)
Lunch
Poster Session II
13:00 - 15:00 (2h)
Poster Session II
Session V : Chemistry of materials and topology control
Tumor on chip models : when microfluidics meets the challenge of cancer biology and clinics
Fabrication of an environmental-controlled human-based colon microphysiological system
Developing tools for organ-on-a-chip technologies
Coffee break
Investigating signalling dynamics using in-vitro models of development and homeostasis
15:00 - 18:00 (3h)
Session V : Chemistry of materials and topology control
Laurent Malaquin
15:00 - 15:40 (40min)
Tumor on chip models : when microfluidics meets the challenge of cancer biology and clinics
Stephanie Descroix
15:40 - 15:55 (15min)
Fabrication of an environmental-controlled human-based colon microphysiological system
Dimitri Hamel
15:55 - 16:35 (40min)
Developing tools for organ-on-a-chip technologies
Nicolaj Gadegaard
16:35 - 17:00 (25min)
Coffee break
17:00 - 18:00 (1h)
Investigating signalling dynamics using in-vitro models of development and homeostasis
Katharina Sonnen
Social Dinner and party
19:30 - 22:30 (3h)
Social Dinner and party
SessionVI : Mechano-biology
Nano-magnetic-instructive tools to engineer and stimulate model tissues
Curvature sensing of epithelial cells under tubular confinement
Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction
Coffee break
From mechanotransductive evolutionary origins of early metazoa to tumorigenic mechanical induction
Polarised contractile jiggling drives the collective amoeboid migration of cancer cell clusters
Uterine Environment Coordinates Trophoblast Migration And Growth During Mouse Embryo Implantation
9:00 - 12:10 (3h10)
SessionVI : Mechano-biology
Morgan Delarue
9:00 - 9:40 (40min)
Nano-magnetic-instructive tools to engineer and stimulate model tissues
Claire Wilhelm
9:40 - 9:55 (15min)
Curvature sensing of epithelial cells under tubular confinement
Caterina Tomba
9:55 - 10:35 (40min)
Cancer-associated fibroblasts actively compress cancer cells and modulate mechanotransduction
Danijela Vignjevic
10:35 - 11:00 (25min)
Coffee break
11:00 - 11:40 (40min)
From mechanotransductive evolutionary origins of early metazoa to tumorigenic mechanical induction
Emmanuel Farge
11:40 - 11:55 (15min)
Polarised contractile jiggling drives the collective amoeboid migration of cancer cell clusters
Diane-Laure Pagès
11:55 - 12:10 (15min)
Uterine Environment Coordinates Trophoblast Migration And Growth During Mouse Embryo Implantation
Vladyslav Bondarenko
Closing remarks
12:10 - 12:30 (20min)
Closing remarks
Lunch
12:30 - 14:00 (1h30)
Lunch